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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Viridepyronone, a new antifungal 6-substituted 2H-pyran-2-one produced by Trichoderma viride.

A new antifungal 6-substituted 2H-pyran-2-one, named viridepyronone, has been isolated from a cultural filtrate of a strain of Trichoderma viride showing antagonistic activity in vitro toward Sclerotium rolfsii, which is the causal agent of crown and stem rot of artichoke. Viridepyronone was characterized as 6-(4-oxopentyl)-2H-pyran-2-one 2 with spectroscopic methods. Bioassays showed that viridepyronone had a good antifungal activity against S. rolfsii, and its minimum inhibitory concentration (over 90% inhibition) was found to be 196 microg/mL. This is the first report of viridepyronone produced by any species of fungi.[1]

References

  1. Viridepyronone, a new antifungal 6-substituted 2H-pyran-2-one produced by Trichoderma viride. Evidente, A., Cabras, A., Maddau, L., Serra, S., Andolfi, A., Motta, A. J. Agric. Food Chem. (2003) [Pubmed]
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