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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Genetic analysis of an ambler class A extended-spectrum beta-lactamase from Capnocytophaga ochracea.

A beta-lactamase gene (cfxA3, 966 bp) was isolated from a beta-lactam-resistant Capnocytophaga ochracea clinical isolate and amplified using primers from the cfxA gene of Bacteroides vulgatus. The MICs of third-generation cephalosporins were much higher than those of the transconjugant Escherichia coli strain. The deduced protein sequence, by comparison with CfxA2 of Prevotella intermedia, had a Y239D substitution and possessed the characteristics of a class A, group 2e beta-lactamase.[1]

References

  1. Genetic analysis of an ambler class A extended-spectrum beta-lactamase from Capnocytophaga ochracea. Jolivet-Gougeon, A., Tamanai-Shacoori, Z., Desbordes, L., Burggraeve, N., Cormier, M., Bonnaure-Mallet, M. J. Clin. Microbiol. (2004) [Pubmed]
 
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