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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Antiproliferative effects of abietane diterpenoids isolated from Hyptis martiusii Benth (Labiatae).

Two abietane diterpenes were isolated from a hexane extract of Hyptis martiusii roots and identified as carnasol 11,14-dihidroxy-8,11,13-abietatrien-7-one. These compounds were tested for their antiproliferative effects on tumor cell lines using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide and on the sea urchin egg development. Both compounds displayed cytotoxic activity against tumor cell lines, but only carnasol was able to inhibit the sea urchin egg cleavages.[1]

References

  1. Antiproliferative effects of abietane diterpenoids isolated from Hyptis martiusii Benth (Labiatae). Costa-Lotufo, L.V., Araújo, E.C., Lima, M.A., Moraes, M.E., Pessoa, C., Silviera, E.R., Moraes, M.O. Die Pharmazie. (2004) [Pubmed]
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