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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Comparison of sympathetic skin response between palmar hyperhidrotic and normal subjects.

Palmar hyperhidrosis is a disorder with excessive sweating. The purpose of this study is to evaluate the autonomic function in palmarhyperhidrotic patients with Sympathetic skin response (SSR) test. In this study SSr was performed for the upper limbs of 20 patients with palmar hyperhidrosis, who did not have any other systemic or localized wrist and palmar disease as "Involved Group" and 28 healthy subject as "Control Group" without any palmar hyperhidrosis, systemic or local disease. The findings indicated a significant difference between latency and amplitude of the two groups (P.V. < 0.001) 95%. Beside, in this study, we observed a direct correlation between severity of symptom and the degree of SSR abnormality. Therefore, involvement of sympathetic nervous system in palmar hyperhidrosis were highly suspected.[1]


  1. Comparison of sympathetic skin response between palmar hyperhidrotic and normal subjects. Kazemi, B., Yahyaii, L., Salmanpour, R., Hadianfard, M.J., Shirzi, Z.R. Electromyography and clinical neurophysiology. (2004) [Pubmed]
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