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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Expression of beta-catenin in developing auditory epithelia of mice.

This study investigated the role of beta-catenin in the development of mouse auditory epithelia. Inner ears obtained from embryonic and newborn mice were used. Expression of beta-catenin was examined together with the expression of Ki-67, a marker for proliferating cells, or myosin VIIa, a marker for differentiated hair cells. In the early phase of development, intense expression of beta-catenin was found in auditory epithelia in which a number of Ki-67-positive cells were identified. Together with a decrease in proliferating cells, the intensity and area of beta-catenin expression were reduced. In addition, during differentiation and maturation of hair cells, the area of beta-catenin expression was further limited. These findings suggest that patterns of expression of beta-catenin are closely linked with the status of auditory epithelia development.[1]

References

  1. Expression of beta-catenin in developing auditory epithelia of mice. Takebayashi, S., Nakagawa, T., Kojima, K., Kim, T.S., Kita, T., Dong, Y., Endo, T., Iguchi, F., Naito, Y., Omori, K., Ito, J. Acta oto-laryngologica. Supplementum. (2004) [Pubmed]
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