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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Lack of activity of orally administered clofazimine against intracellular Mycobacterium tuberculosis in whole-blood culture.

The activity of oral clofazimine against intracellular Mycobacterium tuberculosis was compared to that of ofloxacin in healthy volunteers by the use of whole-blood cultures. Clofazimine was inactive whether it was tested alone or combined with other drugs that are used to treat multidrug-resistant tuberculosis, despite a total dose of 2 g. Kanamycin was the most active drug tested.[1]

References

  1. Lack of activity of orally administered clofazimine against intracellular Mycobacterium tuberculosis in whole-blood culture. Janulionis, E., Sofer, C., Song, H.Y., Wallis, R.S. Antimicrob. Agents Chemother. (2004) [Pubmed]
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