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Miriagou, V. et al.

Miriagou, Tzouvelekis, Villa, Lebessi, Vatopoulos, Carattoli, Tzelepi,

CMY-13, a novel inducible cephalosporinase encoded by an Escherichia coli plasmid.

An IncN plasmid (p541) from Escherichia coli carried a Citrobacter freundii-derived sequence of 4,252 bp which included an ampC-ampR region and was bound by two directly repeated IS26 elements. ampC encoded a novel cephalosporinase (CMY-13) with activity similar to that of CMY-2. AmpR was likely functional as indicated in induction experiments.[1]

References

CMY-13, a novel inducible cephalosporinase encoded by an Escherichia coli plasmid. Miriagou, V., Tzouvelekis, L.S., Villa, L., Lebessi, E., Vatopoulos, A.C., Carattoli, A., Tzelepi, E. Antimicrob. Agents Chemother. (2004) [Pubmed]

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