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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Jefford, M. et al.

Jefford, Kiffer, Somers, Daniel, Davis,

Metastatic basal cell carcinoma: rapid symptomatic response to cisplatin and paclitaxel.

BACKGROUND: Basal cell carcinoma (BCC) is the most common cancer in the community, although it rarely metastasizes. The literature reports less than 100 patients who have received chemotherapy for metastatic BCC. A further case of this rare disease is reported here. The pattern of disease in the reported patient was similar to that described in the literature, but the patient experienced a long period with untreated metastatic disease compared with that in the literature. METHOD: The patient was treated with cisplatin in combination with paclitaxel. Literature review suggests this to be the first report of this combination. RESULTS: Rapid symptomatic response was achieved though late neurotoxicity occurred. CONCLUSION: This regimen is an active combination for the rare patient with metastatic BCC. The combination of carboplatin and paclitaxel causes less neurotoxicity and may therefore be a superior regimen.[1]

References

Metastatic basal cell carcinoma: rapid symptomatic response to cisplatin and paclitaxel. Jefford, M., Kiffer, J.D., Somers, G., Daniel, F.J., Davis, I.D. ANZ journal of surgery. (2004) [Pubmed]

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