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Bisnortriterpenes from Salacia madagascariensis.

A new bisnortriterpene quinone methide, 20-epi-isoiguesterinol (2), and a new 6-oxophenolic triterpene, 6-oxoisoiguesterin (5), as well as two known compounds, isoiguesterin (1) and isoiguesterinol (4), were isolated from the petroleum ether extract of the roots of Salacia madagascariensis. Isoiguesterin (1) and 20-epi-isoiguesterinol (2) showed potent activity against Leishmania.[1]


  1. Bisnortriterpenes from Salacia madagascariensis. Thiem, D.A., Sneden, A.T., Khan, S.I., Tekwani, B.L. J. Nat. Prod. (2005) [Pubmed]
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