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MeSH Review:

Salacia

Kishi, A. et al., Thiem, D.A. et al., Muraoka, O. et al., Yoshikawa, M. et al., Yoshikawa, M. et al., et al.

Setzer, Setzer, Hopper, Moriarity, Lehrman, Niekamp, Morcomb, Bates, McClure, Stessman, Haber, Setzer, Holland, Bozeman, Rozmus, Setzer, Moriarity, Reeb, Vogler, Bates, Haber,

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High impact information on Salacia

Isolation and frontier molecular orbital investigation of bioactive quinone-methide triterpenoids from the bark of Salacia petenensis [1].
The cytotoxic activity of a Salacia liana species from Monteverde, Costa Rica, is due to a high concentration of tingenone [2].
A new bisnortriterpene quinone methide, 20-epi-isoiguesterinol (2), and a new 6-oxophenolic triterpene, 6-oxoisoiguesterin (5), as well as two known compounds, isoiguesterin (1) and isoiguesterinol (4), were isolated from the petroleum ether extract of the roots of Salacia madagascariensis [3].
Structures of new friedelane- and norfriedelane-type triterpenes and polyacylated eudesmane-type sesquiterpene from Salacia chinensis LINN. (S. prinoides DC., Hippocrateaceae) and radical scavenging activities of principal constituents [4].
Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis [5].

Associations of Salacia with chemical compounds

A nitrogen analogue 4 of the naturally occurring sulfonium ion salacinol (1), a potent alpha-glucosidase inhibitor isolated from the Ayruvedic medicine Salacia reticulata, was synthesized and its inhibitory activity against alpha-glucosidase tested [6].
Two new friedelane-type triterpenes, salasones D and E, a new norfriedelane-type triterpene, salaquinone B, and a new polyacylated eudesmane-type sesquiterpene, salasol B, were isolated from the stems of Salacia chinensis LINN [4].
Isoiguesterin, a new antileukemic bisnortriterpene from Salacia madagascariensis [7].
Novel quinone methides from Salacia kraussii with in vitro antimalarial activity [8].
Absolute stereostructure of potent alpha-glucosidase inhibitor, Salacinol, with unique thiosugar sulfonium sulfate inner salt structure from Salacia reticulata [9].

Analytical, diagnostic and therapeutic context of Salacia

Kotalanol, a potent alpha-glucosidase inhibitor with thiosugar sulfonium sulfate structure, from antidiabetic ayurvedic medicine Salacia reticulata [10].

References

Isolation and frontier molecular orbital investigation of bioactive quinone-methide triterpenoids from the bark of Salacia petenensis. Setzer, W.N., Holland, M.T., Bozeman, C.A., Rozmus, G.F., Setzer, M.C., Moriarity, D.M., Reeb, S., Vogler, B., Bates, R.B., Haber, W.A. Planta Med. (2001) [Pubmed]
The cytotoxic activity of a Salacia liana species from Monteverde, Costa Rica, is due to a high concentration of tingenone. Setzer, W.N., Setzer, M.C., Hopper, A.L., Moriarity, D.M., Lehrman, G.K., Niekamp, K.L., Morcomb, S.M., Bates, R.B., McClure, K.J., Stessman, C.C., Haber, W.A. Planta Med. (1998) [Pubmed]
Bisnortriterpenes from Salacia madagascariensis. Thiem, D.A., Sneden, A.T., Khan, S.I., Tekwani, B.L. J. Nat. Prod. (2005) [Pubmed]
Structures of new friedelane- and norfriedelane-type triterpenes and polyacylated eudesmane-type sesquiterpene from Salacia chinensis LINN. (S. prinoides DC., Hippocrateaceae) and radical scavenging activities of principal constituents. Kishi, A., Morikawa, T., Matsuda, H., Yoshikawa, M. Chem. Pharm. Bull. (2003) [Pubmed]
Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis. Morikawa, T., Kishi, A., Pongpiriyadacha, Y., Matsuda, H., Yoshikawa, M. J. Nat. Prod. (2003) [Pubmed]
Synthesis of a nitrogen analogue of salacinol and its alpha-glucosidase inhibitory activity. Muraoka, O., Ying, S., Yoshikai, K., Matsuura, Y., Yamada, E., Minematsu, T., Tanabe, G., Matsuda, H., Yoshikawa, M. Chem. Pharm. Bull. (2001) [Pubmed]
Isoiguesterin, a new antileukemic bisnortriterpene from Salacia madagascariensis. Sneden, A.T. J. Nat. Prod. (1981) [Pubmed]
Novel quinone methides from Salacia kraussii with in vitro antimalarial activity. Figueiredo, J.N., Räz, B., Séquin, U. J. Nat. Prod. (1998) [Pubmed]
Absolute stereostructure of potent alpha-glucosidase inhibitor, Salacinol, with unique thiosugar sulfonium sulfate inner salt structure from Salacia reticulata. Yoshikawa, M., Morikawa, T., Matsuda, H., Tanabe, G., Muraoka, O. Bioorg. Med. Chem. (2002) [Pubmed]
Kotalanol, a potent alpha-glucosidase inhibitor with thiosugar sulfonium sulfate structure, from antidiabetic ayurvedic medicine Salacia reticulata. Yoshikawa, M., Murakami, T., Yashiro, K., Matsuda, H. Chem. Pharm. Bull. (1998) [Pubmed]

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