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Regional localization of human beta-casein gene (CSN2) to 4pter-q21.

Milk proteins are crucial for the development of all newborn mammals. Caseins that constitute the bulk of the protein in mammalian milk have been shown to be members of a multigene family in at least two species. They are among the most rapidly diverging groups of proteins, and their numbers vary widely among species. beta- and kappa-Caseins are the only caseins present in human milk. Using polymerase chain reaction on genomic DNA from somatic cell hybrids, we have localized the human beta-casein gene (CSN2) to 4pter----q21.[1]


  1. Regional localization of human beta-casein gene (CSN2) to 4pter-q21. Menon, R.S., Chang, Y.F., Jeffers, K.F., Jones, C., Ham, R.G. Genomics (1992) [Pubmed]
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