Linking Rap to cell adhesion.
The small GTPase Rap1 is involved in several aspects of cell adhesion, including integrin-mediated cell adhesion and cadherin-mediated cell junction formation. Recently, several effector proteins for Rap1 have been identified providing a clear link between Rap1 and actin dynamics. Furthermore, evidence is accumulating that Rap1 functions in the spatial and temporal control of cell polarity.[1]References
- Linking Rap to cell adhesion. Bos, J.L. Curr. Opin. Cell Biol. (2005) [Pubmed]
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