- Asparagine endopeptidase is not essential for class II MHC antigen presentation but is required for processing of cathepsin L in mice. Maehr, R., Hang, H.C., Mintern, J.D., Kim, Y.M., Cuvillier, A., Nishimura, M., Yamada, K., Shirahama-Noda, K., Hara-Nishimura, I., Ploegh, H.L. J. Immunol. (2005)