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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Surgical management of anterior vaginal wall prolapse: an evidencebased literature review.

The aim of this review is to summarize the available literature on surgical management of anterior vaginal wall prolapse. A Medline search from 1966 to 2004 and a hand-search of conference proceedings of the International Continence Society and International Urogynecological Association from 2001 to 2004 were performed. The success rates for the anterior colporrhaphy vary widely between 37 and 100%. Augmentation with absorbable mesh (polyglactin) significantly increases the success rate for anterior vaginal wall prolapse. Abdominal sacrocolpopexy combined with paravaginal repair significantly reduced the risk for further cystocele surgery compared to anterior colporrhaphy and sacrospinous colpopexy. The abdominal and vaginal paravaginal repair have success rates between 76 and 100%, however, no randomized trials have been performed. There is currently no evidence to recommend the routine use of any graft in primary repairs, and possible improved anatomical out-comes have to be tempered againstcomplications including mesh erosions, infections and dyspareunia.[1]


  1. Surgical management of anterior vaginal wall prolapse: an evidencebased literature review. Maher, C., Baessler, K. Int. Urogynecol. J. Pelvic. Floor. Dysfunct (2006) [Pubmed]
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