- Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases. Mastrangelo, P., Mathews, P.M., Chishti, M.A., Schmidt, S.D., Gu, Y., Yang, J., Mazzella, M.J., Coomaraswamy, J., Horne, P., Strome, B., Pelly, H., Levesque, G., Ebeling, C., Jiang, Y., Nixon, R.A., Rozmahel, R., Fraser, P.E., St George-Hyslop, P., Carlson, G.A., Westaway, D. Proc. Natl. Acad. Sci. U.S.A. (2005)