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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Optical coherence tomography study of tilted optic disk associated with macular detachment.

PURPOSE: To describe the macular findings by optical coherence tomography in both eyes of a patient with tilted optic disk and visual decrease. METHODS: A 35-year-old woman with bilateral tilted optic disk and serous macular detachment was examined by slit-lamp biomicroscopy, fluorescein angiography, indocyanine green angiography and optical coherence tomography (OCT). RESULTS: Fluorescein angiography demonstrated staining of the temporal rim of the staphyloma adjacent to the optic disk and hyperfluorescence of the diffuse pigmentary changes in the papillomacular area. Leakage points and serous macular detachment were not observed. The existing neurosensory detachment at the fovea became evident only by OCT. CONCLUSIONS: The existence of subretinal fluid, which became evident only by OCT, supports the view that OCT could further contribute to the study of the asymptomatic pigmentary lesions of the macula that are present in 11% of eyes with tilted optic disk. The reason for the localized macular detachment remains unclear. Dysfunction of the retinal pigment epithelium (RPE) or leakage of the optic disk staphyloma rim could possibly explain the cause of fluid accumulation in the macula.[1]

References

  1. Optical coherence tomography study of tilted optic disk associated with macular detachment. Theodossiadis, P.G., Grigoropoulos, V., Emfietzoglou, J., Theodossiadis, G.P. Graefes Arch. Clin. Exp. Ophthalmol. (2006) [Pubmed]
 
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