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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Quality of life before and after heart valve surgery is influenced by gender and type of valve.

BACKGROUND: Quality of life (QoL) in valvular surgery may differ according to the underlying pathology and surgical technique used. METHOD: 82 adults undergoing their first elective surgery for valve repair (VP; n = 9) or valve replacement (VR) with a mechanical valve (MVR; n = 57) or bioprosthesis ( BVR; n = 16) were assessed before surgery and three months afterwards. Dependent variables: delta scores (postoperative-preoperative) on QoL measures (Quality of Life Systemic Inventory (QLSI) and SF-36). ANALYSES: Paired t tests and ANCOVAs with age and preoperative QoL scores as covariates. RESULTS: QoL improves after surgery according to most subscales. According to group comparisons, patients with an MVR improve more than those with a BVR on the mental health subscale. In physical roles, patients with an MVR improve while those with a BVR deteriorate. In emotional roles, patients with a VR improve while those with a VP deteriorate. However, they are similar on all other subscales. Women improve more than men on leisure, affectivity and social functioning while the opposite holds true for mental health. CONCLUSION: QoL improves after surgery. However, significant differences between groups are small because of a lack of statistical power.[1]

References

  1. Quality of life before and after heart valve surgery is influenced by gender and type of valve. Taillefer, M.C., Dupuis, G., Hardy, J.F., LeMay, S. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. (2005) [Pubmed]
 
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