- E2F1 induces apoptosis and sensitizes human lung adenocarcinoma cells to death-receptor-mediated apoptosis through specific downregulation of c-FLIP(short). Salon, C., Eymin, B., Micheau, O., Chaperot, L., Plumas, J., Brambilla, C., Brambilla, E., Gazzeri, S. Cell Death Differ. (2006)