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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Antioxidant gene expression in the blood-feeding fly Glossina morsitans morsitans.

We report the characterization of 11 antioxidant genes from the tsetse fly Glossina m. morsitans. Through similarity searches which detected homology we suggest that these genes consist of two superoxide dismutases (one with a putative signal peptide), three thioredoxin peroxidases (one with a putative signal peptide), three peroxiredoxins, one further signal peptide-containing peroxidase with its closest similarity to a glutathione peroxidase, one catalase and one thioredoxin reductase. We describe the changes occurring in the expression levels of these genes during fly development, in different adult tissues, in the adult midgut through the digestive cycle and following trypanosome infection. Overall, nine of the 11 genes studied showed responses to changes in physiological circumstance, with the peroxiredoxin group showing the smallest variations throughout.[1]

References

  1. Antioxidant gene expression in the blood-feeding fly Glossina morsitans morsitans. Munks, R.J., Sant'Anna, M.R., Grail, W., Gibson, W., Igglesden, T., Yoshiyama, M., Lehane, S.M., Lehane, M.J. Insect Mol. Biol. (2005) [Pubmed]
 
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