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Biflavonoids from Lonicera japonica.

Two biflavonoids, 3'-O-methyl loniflavone [5,5'',7,7''-tetrahydroxy 3'-methoxy 4',4'''-biflavonyl ether (1)] and loniflavone [5,5'',7,7'',3'-pentahydroxy 4',4'''-biflavonyl ether (2)] along with luteolin (3) and chrysin (4) were isolated from the leaves of Lonicera japonica. The structures were established on the basis of UV/vis, 1D, 2D NMR (HMQC and HMBC) and ESI-QTOF-MS/MS spectroscopic methods and chemical evidences.[1]


  1. Biflavonoids from Lonicera japonica. Kumar, N., Singh, B., Bhandari, P., Gupta, A.P., Uniyal, S.K., Kaul, V.K. Phytochemistry (2005) [Pubmed]
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