Disease relevance of Lonicera

• We investigated the anti-inflammatory effects of aqueous extract from Lonicera japonica flower (AELJ), a traditional skin rash drug, in lipopolysaccharide (LPS)-induced rat liver sepsis [1].

High impact information on Lonicera

• Based exclusively on hyphenated chromatographic techniques the methanolic extracts of Tilia europea, Urtica dioica, Lonicera periclymenum and Hypericum perforatum are initially screened for their antioxidant components via an on-line DPPH and ABTS radical scavenging technique [2].
• Luteolin is an active compound from the Lonicera japonica (Caprifoliaceae) [3].
• This method provides good reproducibility for the quantification of the major iridoid glucosides in four Lonicera species with overall intra- and inter-day variation of less than 5% and 9%, respectively [4].
• 7-feruloylloganin: an iridoid glucoside from stems of Lonicera insularis [5].
• 13 quinic acid derivatives along with caffeic acid, methyl caffeate, myo-inositol, bis[5-formylfurfuryl] ether and 6,7-dihydroxycoumarin were isolated from the ethanol extract of the flower buds of Lonicera bournei Hemsl., among which 8 compounds were firstly obtained from this genus [6].

Associations of Lonicera with chemical compounds

• The activity of 7-deoxyloganin 7-hydroxylase, an enzyme catalyzing the conversion of 7-deoxyloganin into loganin, was detected in a microsomal preparation from the cell suspension cultures of Lonicera japonica [7].
• Triterpenoid saponins from the aerial parts of Lonicera japonica [8].
• 7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures [7].
• A new iridoid glycoside 6'-O-beta-apiofuranosylsweroside was isolated from the ethanolic extract of the roots of Lonicera quinquelocularis along with the known compounds loganin and sweroside [9].
• Two biflavonoids, 3'-O-methyl loniflavone [5,5'',7,7''-tetrahydroxy 3'-methoxy 4',4'''-biflavonyl ether (1)] and loniflavone [5,5'',7,7'',3'-pentahydroxy 4',4'''-biflavonyl ether (2)] along with luteolin (3) and chrysin (4) were isolated from the leaves of Lonicera japonica [10].

References