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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Prolactin receptors in rat liver: possible induction by prolactin.

A prolactin receptor, present in adult female rat liver, can be induced in males by estrogen. Hypophysectomy diminished receptor levels in the female and rendered males unresponsive to estrogen. A renal pituitary implant blunted the decrease in hypophysectomized females and induced the receptor in hyophysectomized males. The increased receptor level in hypophysectomized males with a renal pituitary implant was preceded by a sustained elevation of circulating prolactin. Our observations suggest that prolactin induces its own receptor.[1]

References

  1. Prolactin receptors in rat liver: possible induction by prolactin. Posner, B.I., Kelly, P.A., Friesen, H.G. Science (1975) [Pubmed]
 
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