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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Milne, A.N. et al.

Milne, Sweeney, O'Riordain, Pauwels, Debiec-Rychter, Offerhaus, Jeffers,

Inflammatory myofibroblastic tumor with ALK/TPM3 fusion presenting as ileocolic intussusception: an unusual presentation of an unusual neoplasm.

Inflammatory myofibroblastic tumor is a rare spindle cell lesion of indeterminate malignant potential occurring in both pulmonary and extrapulmonary tissues. This report describes an unusual presentation of an unusual tumor at an unusual location: an intramural ileal case of inflammatory myofibroblastic tumor presenting with intussusception in a 29-year-old woman. We characterize this tumor through microscopic and ultrastructural analysis, extensive immunohistochemical analysis, ploidy analysis, and Epstein-Barr virus in situ hybridization, and we report the finding of an ALK/TPM3 fusion using fluorescence in situ hybridization.[1]

References

Inflammatory myofibroblastic tumor with ALK/TPM3 fusion presenting as ileocolic intussusception: an unusual presentation of an unusual neoplasm. Milne, A.N., Sweeney, K.J., O'Riordain, D.S., Pauwels, P., Debiec-Rychter, M., Offerhaus, G.J., Jeffers, M. Hum. Pathol. (2006) [Pubmed]

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