Disease relevance of Intussusception

• Formalin-fixed intestinal tissue specimens from 12 Mexican pediatric patients with intussusception were examined for the presence of adenovirus [1].
• EXternal Pelvic REctal SuSpension (Express procedure) for rectal intussusception, with and without rectocele repair [2].
• This leaves the muscularis externa macrophages as the most likely source of local cytokine production under such conditions as postoperative ileus and intussusception in infants, where the muscularis externa appears to be one target of cytokines [3].
• A variety of intestinal complications, including constipation, abdominal pain, palpable cecal masses, intestinal obstruction, intussusception, and volvulus, have been observed beyond the neonatal period in patients with cystic fibrosis (CF) [4].
• Here, we report a case of metastasis of HCC to the small bowel manifested by intussusception [5].

High impact information on Intussusception

• In addition to problems such as intussusception, PJS predisposes to cancers of several sites [6].
• A standard protocol for the procedure was used in all patients, including the intravenous administration of glucagon or placebo (0.05 mg/kg) when the intussusception was encountered [7].
• Inflammatory myofibroblastic tumor with ALK/TPM3 fusion presenting as ileocolic intussusception: an unusual presentation of an unusual neoplasm [8].
• The assays used in this study proved useful for the identification of species C adenoviruses in formalin-fixed specimens from Mexican pediatric patients with intussusception [1].
• Mice were gavaged with normal saline, amoxicillin-clavulanate or azithromycin twice daily for 5 days to assess the influence of enteral antibiotic exposure on intussusception, mesenteric adenopathy and bowel dilation [9].

Chemical compound and disease context of Intussusception

• To test the possibility that lipopolysaccharide induces intussusception by altering motility, its effect on transit index was measured [10].
• This was reduced by a hypaque enema, but the intussusception recurred twice more, being reduced again by hypaque enema and finally having to be reduced by colonoscopy [11].
• Intussusception complicating intestinal intubation with a long Cantor tube: report of four cases [12].
• Cephalosporin use was associated with more than a 20-fold increased risk of intussusception [13].
• The success rates for the ileo-colic intussusceptions with Hartmann's solution reduction and barium enema reduction were 91% (19 of 21) and 55% (12 of 22), respectively (P = .00865) [14].

Biological context of Intussusception

• CONCLUSIONS: Intraperitoneal bacterial wall lipopolysaccharide causes intussusception in mice by disturbing gastrointestinal motility [10].

Anatomical context of Intussusception

• We propose that neutrophils are an intravascular source of VEGF for vessels that undergo angiogenesis by intussusception and elongation [15].
• In one case a multiple concentric ring shadow resulted from an ileocolic intussusception, and in the other a "bull's eye" image was due to an infiltrating carcinoma of the pyloric antrum [16].
• This led to ultrasonography of the gastrointestinal tract that demonstrated typical "bull's eye" pattern within the intussusception process [17].

Gene context of Intussusception

• Glucagon-aided reduction of intussusception [18].
• This is the first time that intussusception of the appendix has been documented in a patient with CF [19].
• Intussusception following resection of Wilms tumor [20].
• We describe 3 patients who presented with coma associated with intussusception [21].
• Moreover, metastatic HCC of the small bowel causing intussusception has not been reported until now [5].

Analytical, diagnostic and therapeutic context of Intussusception

• We feel the association is biologically plausible and alert physicians to consider intussusception in the differential diagnosis of the cocaine-exposed child with vomiting and abdominal pain [22].
• METHODS: Stored neonatal screening blood spots, retrieved from 81 infants with intussusception and from 79 controls, were tested for the presence of the CF delta-F508 gene mutation [23].

References