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Antibacterial activity of polygodial.

Polygodial was found to possess moderate antibacterial activity against gram-positive bacteria including Bacillus subtilis, Staphylococcus aureus and gram-negative bacteria including Escherichia coli and Salmonella choleraesuis with minimum bactericidal concentrations (MBC) of 100 and 100 microg/mL (0.34 mm) and 100 and 50 microg/mL, respectively. The time kill curve study showed that polygodial was bactericidal against B. subtilis and S. choleraesuis. However, there was a difference in its bactericidal action against endospore-forming B. subtilis and food-borne S. choleraesuis.[1]

References

  1. Antibacterial activity of polygodial. Kubo, I., Fujita, K., Lee, S.H., Ha, T.J. Phytotherapy research : PTR. (2005) [Pubmed]
 
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