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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Weill-Marchesani syndrome and secondary glaucoma associated with ectopia lentis.

Weill-Marchesani syndrome (WMS) is a rare systemic connective tissue disorder with the systemic features of short stature, short and stubby hands and feet and stiff joints, especially in the hands. Occasionally, it is associated with heart defects and mental retardation. The main ocular features of WMS are microspherophakia (small and spherical crystalline lens), ectopia lentis (a displaced or malpositioned lens), severe myopia and glaucoma. Rare findings include asymmetric axial lengths associated with presenile vitreous liquefaction. A 14-year-old patient with WMS, who developed a secondary glaucoma and suffered visual loss from the ocular features of WMS, is described. The clinical findings and its successful management are also reported.[1]


  1. Weill-Marchesani syndrome and secondary glaucoma associated with ectopia lentis. Chu, B.S. Clinical & experimental optometry : journal of the Australian Optometrical Association. (2006) [Pubmed]
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