- SLC12A3 (solute carrier family 12 member [sodium/chloride] 3) polymorphisms are associated with end-stage renal disease in diabetic nephropathy. Kim, J.H., Shin, H.D., Park, B.L., Moon, M.K., Cho, Y.M., Hwang, Y.H., Oh, K.W., Kim, S.Y., Lee, H.K., Ahn, C., Park, K.S. Diabetes (2006)