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Thabet, F. et al.

Thabet, Sghiri, Tabarki, Ghedira, Yacoub, Essoussi,

ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil.

Benzylthiouracil has been recently observed to be associated with antineutrophil cytoplasmic antibody-positive vasculitis, resulting in crescentic glomerulonephritis. We report an 8-year-old girl treated with benzylthiouracil for Graves's disease who developed an ANCA-positive vasculitis with pulmonary hemorrhage. She responded to corticosteroids and discontinuation of benzylthiouracil. This represents the first pediatric case of benzylthiouracil-induced diffuse alveolar hemorrhage.[1]

References

ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil. Thabet, F., Sghiri, R., Tabarki, B., Ghedira, I., Yacoub, M., Essoussi, A.S. Eur. J. Pediatr. (2006) [Pubmed]

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