The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Basdene     6-benzyl-2-sulfanylidene-1H- pyrimidin-4-one

Synonyms: AC1LEGI0, NSC-6508, AG-G-35009, SureCN2353689, ALBB-014144, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Basdene


High impact information on Basdene

  • Additionally, 2,6-pyridinediol and 6-benzyl-2-thiouracil have been identified as being potent inhibitors of UrdPase and dThdPase respectively [4].
  • ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil [2].
  • We report an 8-year-old girl treated with benzylthiouracil for Graves's disease who developed an ANCA-positive vasculitis with pulmonary hemorrhage [2].
  • Polarographic (DPP) activity of 6-benzyl-2-thiouracil (6-benzyl-2-mercapto-4-pyrimidinol, BTU) has been examined in a wide range of pH values and it has been discovered that the number and the height of observed peaks depends on composition of supporting electrolyte and concentration of the thiol [5].


  1. Myeloperoxidase-antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis associated with benzylthiouracil therapy: report of the first case. Jarraya, F., Abid, M., Jlidi, R., Mkaouar, K., Mnif, M., Kharrat, M., Charfeddine, K., Kammoun, K., Ben Hmida, M., Hachicha, J. Nephrol. Dial. Transplant. (2003) [Pubmed]
  2. ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil. Thabet, F., Sghiri, R., Tabarki, B., Ghedira, I., Yacoub, M., Essoussi, A.S. Eur. J. Pediatr. (2006) [Pubmed]
  3. Toxic hepatitis induced by antithyroid drugs: four cases including one with cross-reactivity between carbimazole and benzylthiouracil. Sadoul, J.L., Canivet, B., Freychet, P. The European journal of medicine. (1993) [Pubmed]
  4. Structure-activity relationship of ligands of the pyrimidine nucleoside phosphorylases. Niedzwicki, J.G., el Kouni, M.H., Chu, S.H., Cha, S. Biochem. Pharmacol. (1983) [Pubmed]
  5. Pulsepolarographic determination of 6-benzyl-2-thio-uracil. Ciesielski, W., Kasprzak, M. Acta poloniae pharmaceutica. (2000) [Pubmed]
WikiGenes - Universities