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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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BUD2, encoding an S-adenosylmethionine decarboxylase, is required for Arabidopsis growth and development.

Polyamines are implicated in regulating various developmental processes in plants, but their exact roles and how they govern these processes still remain elusive. We report here an Arabidopsis bushy and dwarf mutant, bud2, which results from the complete deletion of one member of the small gene family that encodes S-adenosylmethionine decarboxylases (SAMDCs) necessary for the formation of the indispensable intermediate in the polyamine biosynthetic pathway. The bud2 plant has enlarged vascular systems in inflorescences, roots, and petioles, and an altered homeostasis of polyamines. The double mutant of bud2 and samdc1, a knockdown mutant of another SAMDC member, is embryo lethal, demonstrating that SAMDCs are essential for plant embryogenesis. Our results suggest that polyamines are required for the normal growth and development of higher plants.[1]

References

  1. BUD2, encoding an S-adenosylmethionine decarboxylase, is required for Arabidopsis growth and development. Ge, C., Cui, X., Wang, Y., Hu, Y., Fu, Z., Zhang, D., Cheng, Z., Li, J. Cell Res. (2006) [Pubmed]
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