- Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model. Fan, X., Reneker, L.W., Obrenovich, M.E., Strauch, C., Cheng, R., Jarvis, S.M., Ortwerth, B.J., Monnier, V.M. Proc. Natl. Acad. Sci. U.S.A. (2006)