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Chemical Compound Review

BSPBio_001875     (2R)-2-(1,2-dihydroxyethyl)- 4,5-dihydroxy...

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Disease relevance of ascorbic acid


Psychiatry related information on ascorbic acid


High impact information on ascorbic acid


Chemical compound and disease context of ascorbic acid


Biological context of ascorbic acid


Anatomical context of ascorbic acid


Associations of ascorbic acid with other chemical compounds


Gene context of ascorbic acid


Analytical, diagnostic and therapeutic context of ascorbic acid


  1. Ineffectiveness of ascorbic acid therapy in nephropathic cystinosis. Schneider, J.A., Schlesselman, J.J., Mendoza, S.A., Orloff, S., Thoene, J.G., Kroll, W.A., Godfrey, A.D., Schulman, J.D. N. Engl. J. Med. (1979) [Pubmed]
  2. Vitamin C and the common cold. Findley, T.W. N. Engl. J. Med. (1977) [Pubmed]
  3. A prospective study of the intake of vitamins C, E, and A and the risk of breast cancer. Hunter, D.J., Manson, J.E., Colditz, G.A., Stampfer, M.J., Rosner, B., Hennekens, C.H., Speizer, F.E., Willett, W.C. N. Engl. J. Med. (1993) [Pubmed]
  4. Vitamin E consumption and the risk of coronary heart disease in men. Rimm, E.B., Stampfer, M.J., Ascherio, A., Giovannucci, E., Colditz, G.A., Willett, W.C. N. Engl. J. Med. (1993) [Pubmed]
  5. Vitamin C and iron overload. Herbert, V. N. Engl. J. Med. (1981) [Pubmed]
  6. Premorbid diet and the prognosis of women with breast cancer. Jain, M., Miller, A.B., To, T. J. Natl. Cancer Inst. (1994) [Pubmed]
  7. Ascorbic acid-induced uricosuria. A consequency of megavitamin therapy. Stein, H.B., Hasan, A., Fox, I.H. Ann. Intern. Med. (1976) [Pubmed]
  8. Calcium translocation mechanism in sarcoplasmic reticulum vesicles, deduced from location studies of protein-bound spin labels. Champeil, P., Rigaud, J.L., Gary-Bobo, C.M. Proc. Natl. Acad. Sci. U.S.A. (1980) [Pubmed]
  9. Severe hypovitaminosis C occurring as the result of adoptive immunotherapy with high-dose interleukin 2 and lymphokine-activated killer cells. Marcus, S.L., Dutcher, J.P., Paietta, E., Ciobanu, N., Strauman, J., Wiernik, P.H., Hutner, S.H., Frank, O., Baker, H. Cancer Res. (1987) [Pubmed]
  10. Recycling of vitamin C by a bystander effect. Nualart, F.J., Rivas, C.I., Montecinos, V.P., Godoy, A.S., Guaiquil, V.H., Golde, D.W., Vera, J.C. J. Biol. Chem. (2003) [Pubmed]
  11. High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. A randomized double-blind comparison. Moertel, C.G., Fleming, T.R., Creagan, E.T., Rubin, J., O'Connell, M.J., Ames, M.M. N. Engl. J. Med. (1985) [Pubmed]
  12. Does high-dose ascorbic acid accelerate renal failure? Reznik, V.M., Griswold, W.R., Brams, M.R., Mendoza, S.A. N. Engl. J. Med. (1980) [Pubmed]
  13. Vitamin C and migraine: a case report. Bali, L., Callaway, E. N. Engl. J. Med. (1978) [Pubmed]
  14. Chenodeoxycholic acid, gallstones and vitamin C. Ginter, E. N. Engl. J. Med. (1976) [Pubmed]
  15. Ascorbic-acid transporter Slc23a1 is essential for vitamin C transport into the brain and for perinatal survival. Sotiriou, S., Gispert, S., Cheng, J., Wang, Y., Chen, A., Hoogstraten-Miller, S., Miller, G.F., Kwon, O., Levine, M., Guttentag, S.H., Nussbaum, R.L. Nat. Med. (2002) [Pubmed]
  16. Ascorbic acid and the behavioral response to haloperidol: implications for the action of antipsychotic drugs. Rebec, G.V., Centore, J.M., White, L.K., Alloway, K.D. Science (1985) [Pubmed]
  17. Continuous intravenous deferoxamine infusion. Treatment of secondary hemochromatosis in adults. Blume, K.G., Beutler, E., Chillar, R.K., Fahey, J.L., Sharkoff, D., Zia, P.K. JAMA (1978) [Pubmed]
  18. Modulation of peroxidation in murine melanoma by dietary tyrosine-phenylalanine restriction, levodopa methylester chemotherapy, and sodium ascorbate supplementation. Pierson, H.F., Meadows, G.G. J. Natl. Cancer Inst. (1985) [Pubmed]
  19. Correction of leukocyte function in Chediak-Higashi syndrome by ascorbate. Boxer, L.A., Watanabe, A.M., Rister, M., Besch, H.R., Allen, J., Baehner, R.L. N. Engl. J. Med. (1976) [Pubmed]
  20. Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acid. Vera, J.C., Rivas, C.I., Fischbarg, J., Golde, D.W. Nature (1993) [Pubmed]
  21. The biosynthetic pathway of vitamin C in higher plants. Wheeler, G.L., Jones, M.A., Smirnoff, N. Nature (1998) [Pubmed]
  22. Ascorbic acid treatment corrects the phenotype of a mouse model of Charcot-Marie-Tooth disease. Passage, E., Norreel, J.C., Noack-Fraissignes, P., Sanguedolce, V., Pizant, J., Thirion, X., Robaglia-Schlupp, A., Pellissier, J.F., Fontés, M. Nat. Med. (2004) [Pubmed]
  23. Inhibition by L-ascorbate of bacterial mutagenesis induced by two N-nitroso compounds. Guttenplan, J.B. Nature (1977) [Pubmed]
  24. Metabolism of polycyclic aromatic hydrocarbon derivatives to ultimate carcinogens during lipid peroxidation. Dix, T.A., Marnett, L.J. Science (1983) [Pubmed]
  25. Reassessment of the use of desferrioxamine B in iron overload. Propper, R.D., Shurin, S.B., Nathan, D.G. N. Engl. J. Med. (1976) [Pubmed]
  26. Dietary intake of antioxidants and risk of Alzheimer disease. Engelhart, M.J., Geerlings, M.I., Ruitenberg, A., van Swieten, J.C., Hofman, A., Witteman, J.C., Breteler, M.M. JAMA (2002) [Pubmed]
  27. Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. Morris, M.C., Evans, D.A., Bienias, J.L., Tangney, C.C., Bennett, D.A., Aggarwal, N., Wilson, R.S., Scherr, P.A. JAMA (2002) [Pubmed]
  28. Arthritis associated with calcium oxalate crystals in an anephric patient treated with peritoneal dialysis. Rosenthal, A., Ryan, L.M., McCarty, D.J. JAMA (1988) [Pubmed]
  29. Increasing vitamin C content of plants through enhanced ascorbate recycling. Chen, Z., Young, T.E., Ling, J., Chang, S.C., Gallie, D.R. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  30. A human sodium-dependent vitamin C transporter 2 isoform acts as a dominant-negative inhibitor of ascorbic acid transport. Lutsenko, E.A., Carcamo, J.M., Golde, D.W. Mol. Cell. Biol. (2004) [Pubmed]
  31. Vitamin C inhibits NF-kappa B activation by TNF via the activation of p38 mitogen-activated protein kinase. Bowie, A.G., O'Neill, L.A. J. Immunol. (2000) [Pubmed]
  32. Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor. Xiao, G., Wang, D., Benson, M.D., Karsenty, G., Franceschi, R.T. J. Biol. Chem. (1998) [Pubmed]
  33. Cysteamine therapy for children with nephropathic cystinosis. Gahl, W.A., Reed, G.F., Thoene, J.G., Schulman, J.D., Rizzo, W.B., Jonas, A.J., Denman, D.W., Schlesselman, J.J., Corden, B.J., Schneider, J.A. N. Engl. J. Med. (1987) [Pubmed]
  34. Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer. A controlled trial. Creagan, E.T., Moertel, C.G., O'Fallon, J.R., Schutt, A.J., O'Connell, M.J., Rubin, J., Frytak, S. N. Engl. J. Med. (1979) [Pubmed]
  35. Enhancement of interferon production by poly(rI)-poly(rC) in mouse cell cultures by ascorbic acid. Siegel, B.V. Nature (1975) [Pubmed]
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