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Miniature membrane oxygenator for use in neonatal ECMO.

A new miniature membrane oxygenator (Kuraray KMO, size, 0.3 m2, with a priming volume of 47 ml, compliance of less than 0.1 ml/100 mmHg, and pressure loss of 45 mmHg) with improved gas transfer and mechanical durability was developed and tested. The membrane material is a hollow fiber double layer polyolefin. The testing procedures determined by the AAMI were followed, and the results showed improved O2 and CO2 transfer (70 ml/min and 55 ml/min, respectively). Hemolysis was within acceptable limits, and plasma leakage was undetectable after 7 days of perfusion. Clinical study demonstrated satisfactory performance.[1]

References

  1. Miniature membrane oxygenator for use in neonatal ECMO. Katayama, M., Miyasaka, K., Hirose, I., Shimada, M., Mimura, R., Akasu, H. ASAIO transactions / American Society for Artificial Internal Organs. (1991) [Pubmed]
 
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