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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Modulation of the intestinal flora of mice by treatment with aztreonam and tigemonam.

Oral and parenteral administration of aztreonam and oral administration of tigemonam to conventional mice caused a decrease in the number of aerobic gram-negative rods in the feces. Oral treatment with high doses of aztreonam (greater than or equal to 25 mg/kg/day) and tigemonam (100 mg/kg/day) adversely influenced colonization resistance, whereas oral treatment with lower doses of the monobactams or parenteral treatment with aztreonam did not.[1]

References

  1. Modulation of the intestinal flora of mice by treatment with aztreonam and tigemonam. van Ogtrop, M.L., Guiot, H.F., Mattie, H., van Strijen, E., Sekh, B.R., van Furth, R. Antimicrob. Agents Chemother. (1991) [Pubmed]
 
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