PUVA-induced lymphomatoid papulosis in a patient with mycosis fungoides.
The occurrence of lymphomatoid papulosis in patients with cutaneous lymphoma, particularly mycosis fungoides, has been described in medical literature. A 68-year-old woman affected by mycosis fungoides in the plaque stage noticed that multiple papulonodular lesions of lymphomatoid papulosis developed suddenly after a few sessions of PUVA therapy. The PUVA induction of lymphomatoid papulosis was confirmed by the appearance of new lesions after a second cycle of PUVA exposure on a limited area of the body. Complete regression of all PUVA-induced lymphomatoid papulosis lesions was achieved within a few weeks with oral prednisone and topical steroids. During the entire treatment the patches and plaques of mycosis fungoides persisted unchanged.[1]References
- PUVA-induced lymphomatoid papulosis in a patient with mycosis fungoides. Wolf, P., Cerroni, L., Smolle, J., Kerl, H. J. Am. Acad. Dermatol. (1991) [Pubmed]
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