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Flow cytometric detection of jellyfish venom induced cytotoxicity.

Crude venoms of three poisonous jellyfish produce membrane depolarization as determined by the loss of fluorescence intensity of 3,3'-dipentyloxacarbocyanine iodide loaded cells measured by flow cytometry. This method for detecting jellyfish cytotoxicity was reproducible and more sensitive than mouse lethality assays.[1]

References

  1. Flow cytometric detection of jellyfish venom induced cytotoxicity. Ordóñez, J.V., Rubinstein, H.M., Burnett, J.W. Toxicon (1990) [Pubmed]
 
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