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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Acquired pendular nystagmus in toluene addiction.

We studied the ocular motor abnormalities in 4 patients chronically addicted to sniffing glue containing toluene. They showed acquired pendular nystagmus with horizontal and vertical components. One patient also showed saccadic oscillations. The pendular nystagmus may be a manifestation of a disturbance in brainstem-cerebellar connections secondary to the toxic effect of toluene on white matter.[1]


  1. Acquired pendular nystagmus in toluene addiction. Maas, E.F., Ashe, J., Spiegel, P., Zee, D.S., Leigh, R.J. Neurology (1991) [Pubmed]
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