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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Pathophysiologic mechanisms, diagnosis, and management of dapsone-induced methemoglobinemia.

Dapsone is a leprostatic agent commonly prescribed for the treatment of patients with leprosy, malaria, and a variety of blistering skin diseases, including dermatitis herpetiformis. Methemoglobinemia, a potentially life-threatening condition in which the oxygen-carrying capacity of blood in body tissues is reduced, is a known adverse effect of dapsone use. The authors report a case of dapsone-induced methemoglobinemia observed in the emergency department during routine workup for contact dermatitis in a patient with celiac disease. The pathophysiologic mechanisms, diagnosis, and management of dapsone-induced methemoglobinemia are discussed.[1]

References

  1. Pathophysiologic mechanisms, diagnosis, and management of dapsone-induced methemoglobinemia. Ashurst, J.V., Wasson, M.N., Hauger, W., Fritz, W.T. J. Am. Osteopath. Assoc (2010) [Pubmed]
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