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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Lack of protective effect of thromboxane synthetase inhibitor (CGS-13080) on single dose radiated canine intestine.

The effect of a thromboxane A2 synthetase inhibitor (CGS-13080) on canine intestine was studied using a single dose of radiation, and radioactive microspheres were used to determine resultant blood flow. Thromboxane A2 causes vasospasm and platelet aggregation and may play a dominant role in radiation injury. However, there was no effect on the intestinal blood flow diminution occurring after radiation in this laboratory model using this thromboxane A2 synthetase inhibitor.[1]

References

  1. Lack of protective effect of thromboxane synthetase inhibitor (CGS-13080) on single dose radiated canine intestine. Barter, J.F., Marlow, D., Kamath, R.K., Harbert, J., Torrisi, J.R., Barnes, W.A., Potkul, R.K., Newsome, J.T., Delgado, G. Gynecol. Oncol. (1991) [Pubmed]
 
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