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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

The p38 and p34 polypeptides of growth cone particle membranes are the alpha- and beta-subunits of G proteins.

Growth cone particle (GCP) membranes prepared from fetal day 17 rat brain are comprised of 5 major polypeptides as analyzed by SDS-PAGE: tubulin (p52), actin (p42), pp46/GAP-43 and two unidentified species, p38 and p34. Antibodies specific for the alpha- and beta-subunits of G proteins recognize p38 and p34, respectively, on immunoblots following one- and two-dimensional electrophoretic separation. That G protein subunits comprise major species of GCP membrane-associated polypeptides suggests a role for G proteins in transmembrane signaling in nerve growth cones.[1]

References

  1. The p38 and p34 polypeptides of growth cone particle membranes are the alpha- and beta-subunits of G proteins. Edmonds, B.T., Moomaw, C.R., Hsu, J.T., Slaughter, C., Ellis, L. Brain Res. Dev. Brain Res. (1990) [Pubmed]
 
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