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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

The in vitro biosynthesis of dhurrin, the cyanogenic glycoside of Sorghum bicolor.

A microsomal fraction from seedlings of Sorghum bicolor (Linn) Moench has been shown to catalyze the conversion of L-tyrosine to p-hydroxymandelonitrile via p-hydroxyphenylacetaldoxime. This transformation is consistent with the general pathway for cyanogenic glycoside biosynthesis proposed on the basis of in vivo experiments. When the microsomal fraction was combined with a protein fraction from the soluble portion of the cell and uridine diphosphate glucose, it was possible to demonstrate the synthesis of the cyanogenic glycoside dhurrin from L-tyrosine.[1]

References

  1. The in vitro biosynthesis of dhurrin, the cyanogenic glycoside of Sorghum bicolor. MacFarlane, I.J., Lees, E.M., Conn, E.E. J. Biol. Chem. (1975) [Pubmed]
 
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