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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Cerebral amyloid angiopathy: diagnosis by MRI and brain biopsy.

We report the case of an intellectually deteriorating 66-year-old man who presented with an epileptic seizure. CT of the brain suggested a low-grade astrocytoma, but MRI showed multiple punctate hemorrhagic lesions and a demyelination of vascular origin. Brain biopsy revealed depositions of amyloid in cortical and meningeal arteries. MRI may be of value in diagnosing cerebral amyloid angiopathy associated with leukoencephalopathy and petechial hemorrhages.[1]


  1. Cerebral amyloid angiopathy: diagnosis by MRI and brain biopsy. Hendricks, H.T., Franke, C.L., Theunissen, P.H. Neurology (1990) [Pubmed]
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