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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Concentrations of cefixime in bronchial mucosa and sputum after three oral multiple dose regimens.

In a study of 58 patients the concentrations of cefixime, a new oral cephem antibiotic, in bronchial mucosa were 35-40% of the concentrations found in simultaneously collected serum samples. The antibiotic was often undetectable in sputum despite a highly sensitive assay.[1]

References

  1. Concentrations of cefixime in bronchial mucosa and sputum after three oral multiple dose regimens. Baldwin, D.R., Andrews, J.M., Ashby, J.P., Wise, R., Honeybourne, D. Thorax (1990) [Pubmed]
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