Chemical Compound Review:
LS-149976 7-[[(E)-2-(2-amino-1,3- thiazol-4-yl)-4...
Synonyms:
LS-187379, AC1O44MA, C15H14N4O6S2
- Site-saturation studies of beta-lactamase: production and characterization of mutant beta-lactamases with all possible amino acid substitutions at residue 71. Schultz, S.C., Richards, J.H. Proc. Natl. Acad. Sci. U.S.A. (1986)
- In vitro activity of BMY-28100, a new oral cephalosporin. Eliopoulos, G.M., Reiszner, E., Wennersten, C., Moellering, R.C. Antimicrob. Agents Chemother. (1987)
- Comparative in vitro activity of ceftibuten (Sch 39720) against bacterial enteropathogens. Shawar, R., LaRocco, M., Cleary, T.G. Antimicrob. Agents Chemother. (1989)
- Alternative activity of beta-lactam antibiotics against methicillin- and cephem-resistant Staphylococcus aureus in the presence of respiratory tract mucus. Igarashi, K., Matsuyama, T. J. Infect. Dis. (1990)
- Activities of ceftobiprole, a novel broad-spectrum cephalosporin, against Haemophilus influenzae and Moraxella catarrhalis. Bogdanovich, T., Clark, C., Ednie, L., Lin, G., Smith, K., Shapiro, S., Appelbaum, P.C. Antimicrob. Agents Chemother. (2006)
- Comparison of the efficacy and tolerability of once-daily ceftibuten and twice-daily cefprozil in the treatment of children with acute otitis media. Blumer, J.L., Forti, W.P., Summerhouse, T.L. Clinical therapeutics. (1996)
- Relation of structural properties of beta-lactam antibiotics to antibacterial activity. Neu, H.C. Am. J. Med. (1985)
- beta-lactam antibiotics. Novel synthetic routes to cephem-ring system from beta-lactam thiazolines via hydrazinothioazetidinones. Franceschi, G., Foglio, M., Masi, P., Suarato, A., Palamidessi, G., Bernardi, L., Arcamone-Cainelli, G. J. Am. Chem. Soc. (1977)
- In vitro activities of piperacillin against beta-lactamase-negative ampicillin-resistant Haemophilus influenzae. Morikawa, Y., Kitazato, M., Mitsuyama, J., Mizunaga, S., Minami, S., Watanabe, Y. Antimicrob. Agents Chemother. (2004)
- Azithromycin. A review of its use in paediatric infectious diseases. Langtry, H.D., Balfour, J.A. Drugs (1998)
- Nosocomial spread of cephem-resistant Escherichia coli strains carrying multiple Toho-1-like beta-lactamase genes. Yagi, T., Kurokawa, H., Senda, K., Ichiyama, S., Ito, H., Ohsuka, S., Shibayama, K., Shimokata, K., Kato, N., Ohta, M., Arakawa, Y. Antimicrob. Agents Chemother. (1997)
- Penetration of ceftibuten into middle ear fluid. Lin, C., Kumari, P., Perrotta, R.J., Reidenberg, B.E. Antimicrob. Agents Chemother. (1996)
- Antimicrobial activity, spectrum, and recommendations for disk diffusion susceptibility testing of ceftibuten (7432-S; SCH 39720), a new orally administered cephalosporin. Jones, R.N., Barry, A.L. Antimicrob. Agents Chemother. (1988)
- Optimal times above MICs of ceftibuten and cefaclor in experimental intra-abdominal infections. Onyeji, C.O., Nicolau, D.P., Nightingale, C.H., Quintiliani, R. Antimicrob. Agents Chemother. (1994)
- Production of low-affinity penicillin-binding protein by low- and high-resistance groups of methicillin-resistant Staphylococcus aureus. Murakami, K., Nomura, K., Doi, M., Yoshida, T. Antimicrob. Agents Chemother. (1987)
- The relationship between an increase in beta-lactamase activity after oral administration of three new cephalosporins and protection against intestinal ecological disturbances. Edlund, C., Stark, C., Nord, C.E. J. Antimicrob. Chemother. (1994)
- Multiple-dose pharmacokinetics of ceftibuten in healthy volunteers. Lin, C., Radwanski, E., Affrime, M., Cayen, M.N. Antimicrob. Agents Chemother. (1995)
- Effect of protein binding in serum on therapeutic efficacy of cephem antibiotics. Tawara, S., Matsumoto, S., Kamimura, T., Goto, S. Antimicrob. Agents Chemother. (1992)
- Ceftibuten pharmacokinetics and pharmacodynamics. Focus on paediatric use. Kearns, G.L., Young, R.A. Clinical pharmacokinetics. (1994)
- Clinical pharmacokinetics of newer cephalosporins. Klepser, M.E., Marangos, M.N., Patel, K.B., Nicolau, D.P., Quintiliani, R., Nightingale, C.H. Clinical pharmacokinetics. (1995)
- Pharmacokinetics of cephem antibiotics in exudate of pelvic retroperitoneal space after radical hysterectomy and pelvic lymphadenectomy. Ito, K., Hayasaki, M., Tamaya, T. Antimicrob. Agents Chemother. (1990)
- Concentrations of cefixime in bronchial mucosa and sputum after three oral multiple dose regimens. Baldwin, D.R., Andrews, J.M., Ashby, J.P., Wise, R., Honeybourne, D. Thorax (1990)
- Cephem sulfones as inactivators of human leukocyte elastase. 5. 7 alpha-Methoxy- and 7 alpha-chloro-1,1-dioxocephem 4-ketones. Alpegiani, M., Bissolino, P., Corigli, R., Del Nero, S., Perrone, E., Rizzo, V., Sacchi, N., Cassinelli, G., Franceschi, G., Baici, A. J. Med. Chem. (1994)
- Summary of clinical experience with cefpodoxime proxetil in adults in Japan. Kumazawa, J. Drugs (1991)
- In vitro activity of Bay v 3522, a new cephalosporin, compared with activities of other agents. Wise, R., Andrews, J.M., Ashby, J.P., Thornber, D. Antimicrob. Agents Chemother. (1990)
- In vitro and in vivo antibacterial properties of FK 027, a new orally active cephem antibiotic. Kamimura, T., Kojo, H., Matsumoto, Y., Mine, Y., Goto, S., Kuwahara, S. Antimicrob. Agents Chemother. (1984)
- In vitro activities of ICI 194008 and ICI 193428, two new cephem antimicrobial agents. Allan, J.D., Eliopoulos, G.M., Reiszner, E., Moellering, R.C. Antimicrob. Agents Chemother. (1987)
- Ceftibuten (7432-S, SCH 39720): comparative antimicrobial activity against 4735 clinical isolates, beta-lactamase stability and broth microdilution quality control guidelines. Jones, R.N., Barry, A.L. Eur. J. Clin. Microbiol. Infect. Dis. (1988)
- Interaction of anionic cephalosporins with the intestinal and renal peptide transporters PEPT 1 and PEPT 2. Ganapathy, M.E., Prasad, P.D., Mackenzie, B., Ganapathy, V., Leibach, F.H. Biochim. Biophys. Acta (1997)
- The meaning of the development of flomoxef and clinical experience in Japan. Ito, M., Ishigami, T. Infection (1991)
- Mechanism of inhibition of the PC1 beta-lactamase of Staphylococcus aureus by cephalosporins: importance of the 3'-leaving group. Faraci, W.S., Pratt, R.F. Biochemistry (1985)
- Clinical evaluation of ceftibuten in gonorrhea. A pilot study in Hong Kong. Chong, L.Y., Cheung, W.M., Leung, C.S., Yu, C.W., Chan, L.Y. Sexually transmitted diseases. (1998)