The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 

Evaluation of epithelial tissue plasminogen activator as a thrombolytic agent in a rabbit model of venous thrombosis.

The thrombolytic effect of guinea pig keratocyte plasminogen activator was evaluated in rabbits with experimental jugular vein thrombosis and compared with human melanoma activator. Both the activators were infused locally at two dose levels in groups of three rabbits. Infusion of 6,000 and 16,000 I.U./rabbit over 4 hr resulted in 43 and 62% lysis with guinea pig keratocyte activator whereas melanoma activator induced 59 and 66% lysis with 6,000 and 12,000 I.U./rabbit. Thrombolysis with both these activators was not associated with systemic activation of the fibrinolytic system or fibrinogen breakdown. It is concluded that the guinea pig keratocyte activator is a specific thrombolytic agent with an in vivo potency very similar to the melanoma activator.[1]

References

  1. Evaluation of epithelial tissue plasminogen activator as a thrombolytic agent in a rabbit model of venous thrombosis. Electricwala, A., Emeis, J.J., Atkinson, T. J. Pharmacol. Exp. Ther. (1986) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities