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MeSH Review

Jugular Veins

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Disease relevance of Jugular Veins


Psychiatry related information on Jugular Veins


High impact information on Jugular Veins

  • Tissue plasminogen activator was introduced continuously via the right jugular vein [9].
  • Pulmonary emboli were generated in mice by injection, through the right jugular vein, of a human platelet-rich plasma clot radiolabelled with technetium-99m-labelled antifibrin antibodies [9].
  • Infusion of purified kallistatin (0.07-1.42 nmol/kg) into cannulated rat jugular vein produced a 20-85 mmHg reduction of blood pressure in a dose-dependent manner [10].
  • Inactivation of u-PAR was confirmed by the absence of binding of rabbit anti-murine u-PAR or of an aminoterminal fragment of murine u-PA (mu-PA.1-48) to u-PAR-1- embryonic fibroblasts and macrophages. u-PAR-1- mice displayed normal lysis of a murine plasma clot injected via the jugular vein [11].
  • Animals in the first treatment group were each given 22.5 MBq 153Sm-EDTMP via the jugular vein (day 3 or 10), followed by 18.5 mg/kg melphalan (maximum tolerated dose) given intraperitoneally 5 days later (day 8 or 15) and syngeneic BMT another 2 days later (day 10 or 17) [12].

Chemical compound and disease context of Jugular Veins


Biological context of Jugular Veins


Anatomical context of Jugular Veins

  • After 7 days of continuous infusion of amino acid-glucose mixture via a gastric or jugular vein catheter, pharmacokinetic parameters were determined after 40 mg/kg of pentobarbital was given orally or into the portal or femoral vein [23].
  • Thrombolysis and reocclusion in experimental jugular vein and coronary artery thrombosis. Effects of a plasminogen activator inhibitor type 1-neutralizing monoclonal antibody [24].
  • Experimental obstruction of branches of the pulmonary artery was induced in 19 anesthetized dogs by inflation of balloon-tipped catheters (8-12 mm in diameter), injection of radiopaque silicone spheres (0.5-4.0 mm), and embolization with barium-impregnated autologous blood clots (1-5 mm) via the right external jugular vein [25].
  • Rats were fitted with bile duct and jugular vein catheters while anesthetized with diethyl ether, ketamine or pentobarbital [26].
  • Higher responses, for all cell types, were found when interleukin-2 was administered regionally, that is, through the hepatic artery rather than through the systemic route (jugular vein), although the differences were not statistically significant [27].

Associations of Jugular Veins with chemical compounds

  • We took blood samples from internal jugular veins in 101 healthy men, to assess the relation between concentration of serotonin metabolite in these samples and weather conditions and season [28].
  • Two to ten days after the initial procedure, shunted and sham-operated controls received a continuous infusion of nitroglycerin into a jugular vein, the ileocolic vein, or intrajejunally [29].
  • METHODS: Using catheters placed in an internal jugular vein, we estimated the release of brain monoamine neurotransmitters in 19 healthy volunteers and in 9 patients with nonbipolar depressive illness refractory to medication at rest and following intravenous desipramine hydrochloride [30].
  • Half of the animals also were instrumented with subcutaneously placed osmotic pumps and catheters that delivered heparin (300 units/h) into the external jugular vein [31].
  • Thrombi containing either 16 microg r-apo(a), 8 microg r-apo(a), or vehicle (HEPES-buffered saline, control) were formed in the jugular veins of a rabbit and showed significantly reduced endogenous thrombolysis after 60 minutes in a dose-dependent fashion, ID 2.7+/-0.9% and 4.6+/-1.8%, respectively, versus 7.4+/-1.6% of that of the control [32].

Gene context of Jugular Veins

  • PAI-1 and VN also affected the time to occlusion after injury to the jugular vein [33].
  • The primary aim of the present study was to compare plasma levels of SP, NPY and VIP in external jugular vein between patients with chronic tension-type headache and healthy controls [34].
  • METHODS: Hearts of p53-/- or p53+/+ C57BL/6J mice were grafted to the neck carotid artery and jugular vein of BALB/c mice using a cuff technique [35].
  • METHODS: Porcine internal jugular veins were transduced passively with 1 x 10(11) particles of an adenoviral vector carrying either the human iNOS (AdiNOS) or beta-galactosidase (AdlacZ) cDNA for 30 minutes and then interposed into the carotid artery circulation [36].
  • DESIGN: We prospectively collected blood samples from the inferior petrosal sinus and internal jugular vein of consecutive patients with ACTH-dependent CS [37].

Analytical, diagnostic and therapeutic context of Jugular Veins


  1. Fatal cardiac tamponade. Occurrence with other complications after left internal jugular vein catheterization. Sheep, R.E., Guiney, W.B. JAMA (1982) [Pubmed]
  2. Influence of the fast-acting inhibitor of plasminogen activator on in vivo thrombolysis induced by tissue-type plasminogen activator in rabbits. Interference of tissue-derived components. Colucci, M., Paramo, J.A., Stassen, J.M., Collen, D. J. Clin. Invest. (1986) [Pubmed]
  3. Bilateral sampling of the internal jugular vein to distinguish between mechanisms of adrenocorticotropic hormone-dependent Cushing syndrome. Doppman, J.L., Oldfield, E.H., Nieman, L.K. Ann. Intern. Med. (1998) [Pubmed]
  4. Genetic modification of the vessel wall. Comparison of surgical and catheter-based techniques for delivery of recombinant adenovirus. Willard, J.E., Landau, C., Glamann, D.B., Burns, D., Jessen, M.E., Pirwitz, M.J., Gerard, R.D., Meidell, R.S. Circulation (1994) [Pubmed]
  5. Osmotic responsiveness and cross talk involving oxytocin, but not vasopressin or amino acids, between the supraoptic nuclei in virgin and lactating rats. Neumann, I., Landgraf, R., Bauce, L., Pittman, Q.J. J. Neurosci. (1995) [Pubmed]
  6. Accuracy of the one-point in vivo calibration of "wired" glucose oxidase electrodes implanted in jugular veins of rats in periods of rapid rise and decline of the glucose concentration. Schmidtke, D.W., Heller, A. Anal. Chem. (1998) [Pubmed]
  7. High chromium yeast supplementation improves glucose tolerance in pigs by decreasing hepatic extraction of insulin. Guan, X., Matte, J.J., Ku, P.K., Snow, J.L., Burton, J.L., Trottier, N.L. J. Nutr. (2000) [Pubmed]
  8. Continuous intravenous infusion of phencyclidine in unrestrained rats results in the rapid induction of tolerance and physical dependence. Spain, J.W., Klingman, G.I. J. Pharmacol. Exp. Ther. (1985) [Pubmed]
  9. Antifibrinolytic activity of apolipoprotein(a) in vivo: human apolipoprotein(a) transgenic mice are resistant to tissue plasminogen activator-mediated thrombolysis. Palabrica, T.M., Liu, A.C., Aronovitz, M.J., Furie, B., Lawn, R.M., Furie, B.C. Nat. Med. (1995) [Pubmed]
  10. Kallistatin is a potent new vasodilator. Chao, J., Stallone, J.N., Liang, Y.M., Chen, L.M., Wang, D.Z., Chao, L. J. Clin. Invest. (1997) [Pubmed]
  11. Generation and characterization of urokinase receptor-deficient mice. Dewerchin, M., Nuffelen, A.V., Wallays, G., Bouché, A., Moons, L., Carmeliet, P., Mulligan, R.C., Collen, D. J. Clin. Invest. (1996) [Pubmed]
  12. Radiopharmaceutical therapy of 5T33 murine myeloma by sequential treatment with samarium-153 ethylenediaminetetramethylene phosphonate, melphalan, and bone marrow transplantation. Turner, J.H., Claringbold, P.G., Manning, L.S., O'Donoghue, H.L., Berger, J.D., Glancy, R.J. J. Natl. Cancer Inst. (1993) [Pubmed]
  13. Plasma concentration of adenosine during normoxia and moderate hypoxia in humans. Saito, H., Nishimura, M., Shinano, H., Makita, H., Tsujino, I., Shibuya, E., Sato, F., Miyamoto, K., Kawakami, Y. Am. J. Respir. Crit. Care Med. (1999) [Pubmed]
  14. The comparative effects of recombinant hirudin (CGP 39393) and standard heparin on thrombus growth in rabbits. Agnelli, G., Pascucci, C., Cosmi, B., Nenci, G.G. Thromb. Haemost. (1990) [Pubmed]
  15. Variable effects of radiological contrast media on thrombus growth in a rabbit jugular vein thrombosis model. Levi, M., Biemond, B.J., Sturk, A., Hoek, J., ten Cate, J.W. Thromb. Haemost. (1991) [Pubmed]
  16. Manipulation of the local thromboxane and prostacyclin balance in vivo by the antithrombotic compounds dazoxiben, acetylsalicylic acid and nafazatrom. Deckmyn, H., Van Houtte, E., Verstraete, M., Vermylen, J. Biochem. Pharmacol. (1983) [Pubmed]
  17. Liver as a focus of impaired oxygenation and cytokine production in a porcine model of endotoxicosis. Bathe, O.F., Rudston-Brown, B., Chow, A.W., Phang, P.T. Crit. Care Med. (1998) [Pubmed]
  18. Induction of monocyte chemoattractant protein-1 in the small veins of the ischemic and reperfused canine myocardium. Kumar, A.G., Ballantyne, C.M., Michael, L.H., Kukielka, G.L., Youker, K.A., Lindsey, M.L., Hawkins, H.K., Birdsall, H.H., MacKay, C.R., LaRosa, G.J., Rossen, R.D., Smith, C.W., Entman, M.L. Circulation (1997) [Pubmed]
  19. Genetic engineering of vein grafts resistant to atherosclerosis. Mann, M.J., Gibbons, G.H., Kernoff, R.S., Diet, F.P., Tsao, P.S., Cooke, J.P., Kaneda, Y., Dzau, V.J. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
  20. Intraluteal infusion of a prostaglandin synthesis inhibitor, sodium meclofenamate, causes premature luteolysis in rhesus monkeys. Sargent, E.L., Baughman, W.L., Novy, M.J., Stouffer, R.L. Endocrinology (1988) [Pubmed]
  21. Affects of hirudin and heparin on the binding of new fibrin to the thrombus in t-PA treated rabbits. Agnelli, G., Pascucci, C., Cosmi, B., Nenci, G.G. Thromb. Haemost. (1991) [Pubmed]
  22. Secretory patterns of progesterone and gonadotropins in the ovarian branch of the ovarian vein and the jugular vein during and around the second trimester of pregnancy in the cow. Hamrick, C.D., Gimenez, T. Biol. Reprod. (1985) [Pubmed]
  23. Alterations in pentobarbital pharmacokinetics in response to parenteral and enteral alimentation in the rat. Knodell, R.G., Spector, M.H., Brooks, D.A., Keller, F.X., Kyner, W.T. Gastroenterology (1980) [Pubmed]
  24. Thrombolysis and reocclusion in experimental jugular vein and coronary artery thrombosis. Effects of a plasminogen activator inhibitor type 1-neutralizing monoclonal antibody. Biemond, B.J., Levi, M., Coronel, R., Janse, M.J., ten Cate, J.W., Pannekoek, H. Circulation (1995) [Pubmed]
  25. Detection of experimental pulmonary emboli in dogs by sequential positron imaging after inhalation of 15O-carbon dioxide. Nichols, A.B., Cochavi, S., Moore, R.H., Beller, G.A. Circ. Res. (1978) [Pubmed]
  26. Effects of anesthetic agents on bile pigment excretion in the rat. Gourley, G.R., Mogilevsky, W., Arend, R.A., Siegel, F.L., Odell, G.B. Hepatology (1985) [Pubmed]
  27. Electron microscopic observations on the accumulation of large granular lymphocytes (pit cells) and Kupffer cells in the liver of rats treated with continuous infusion of interleukin-2. Bouwens, L., Marinelli, A., Kuppen, P.J., Eggermont, A.M., van de Velde, C.J., Wisse, E. Hepatology (1990) [Pubmed]
  28. Effect of sunlight and season on serotonin turnover in the brain. Lambert, G.W., Reid, C., Kaye, D.M., Jennings, G.L., Esler, M.D. Lancet (2002) [Pubmed]
  29. Portal-systemic shunting and the hemodynamic effects of nitroglycerin in the rat. Blei, A.T., O'Reilly, D.J., Gottstein, J. Gastroenterology (1984) [Pubmed]
  30. Reduced brain norepinephrine and dopamine release in treatment-refractory depressive illness: evidence in support of the catecholamine hypothesis of mood disorders. Lambert, G., Johansson, M., Agren, H., Friberg, P. Arch. Gen. Psychiatry (2000) [Pubmed]
  31. Heparin accelerates coronary collateral development in a porcine model of coronary artery occlusion. Carroll, S.M., White, F.C., Roth, D.M., Bloor, C.M. Circulation (1993) [Pubmed]
  32. Apolipoprotein(a) attenuates endogenous fibrinolysis in the rabbit jugular vein thrombosis model in vivo. Biemond, B.J., Friederich, P.W., Koschinsky, M.L., Levi, M., Sangrar, W., Xia, J., Büller, H.R., ten Cate, J.W. Circulation (1997) [Pubmed]
  33. Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice. Eitzman, D.T., Westrick, R.J., Nabel, E.G., Ginsburg, D. Blood (2000) [Pubmed]
  34. Plasma levels of substance P, neuropeptide Y and vasoactive intestinal polypeptide in patients with chronic tension-type headache. Ashina, M., Bendtsen, L., Jensen, R., Ekman, R., Olesen, J. Pain (1999) [Pubmed]
  35. Prolonged survival of heart allografts from p53-deficient mice. Hu, Y., Zou, Y., Hala, M., Dietrich, H., Wick, G., Xu, Q. Transplantation (2000) [Pubmed]
  36. Adenovirus-mediated gene transfer of human inducible nitric oxide synthase in porcine vein grafts inhibits intimal hyperplasia. Kibbe, M.R., Tzeng, E., Gleixner, S.L., Watkins, S.C., Kovesdi, I., Lizonova, A., Makaroun, M.S., Billiar, T.R., Rhee, R.Y. J. Vasc. Surg. (2001) [Pubmed]
  37. Internal jugular vein sampling in adrenocorticotropic hormone-dependent Cushing's syndrome: a comparison with inferior petrosal sinus sampling. Erickson, D., Huston, J., Young, W.F., Carpenter, P.C., Wermers, R.A., Bonelli, F.S., Powell, C.C. Clin. Endocrinol. (Oxf) (2004) [Pubmed]
  38. Effect of verapamil on malignant tissue blood flow in SMT-2A tumor-bearing rats. Kaelin, W.G., Shrivastav, S., Shand, D.G., Jirtle, R.L. Cancer Res. (1982) [Pubmed]
  39. In situ assembled mass-transport controlling micromembranes and their application in implanted amperometric glucose sensors. Chen, T., Friedman, K.A., Lei, I., Heller, A. Anal. Chem. (2000) [Pubmed]
  40. Reduction of experimental myocardial infarct size by infusion of lactosylphenyl Trolox. Wu, T.W., Wu, J., Zeng, L.H., Sugiyama, H., Mickle, D.A., Au, J.X. Cardiovasc. Res. (1993) [Pubmed]
  41. Biological activities of photoaffinity labeling analogues of kinins and their irreversible effects on kinin receptors. Escher, E., Laczkó, E., Guillemette, G., Regoli, D. J. Med. Chem. (1981) [Pubmed]
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