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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Effects of endothelin-1 and endothelin-3 on blood pressure in conscious hypertensive rats.

The vasopressor potencies of endothelin (ET) in SHR, DOC, and CLIP hypertensive rats were determined. Rat endothelin ( ET-3) showed greater vasopressor activity in SHR. The mechanism of this greater potency and the pathogenesis of hypertension in SHR remains to be investigated.[1]

References

  1. Effects of endothelin-1 and endothelin-3 on blood pressure in conscious hypertensive rats. Watanabe, T.X., Kumagaye, S., Nishio, H., Nakajima, K., Kimura, T., Sakakibara, S. J. Cardiovasc. Pharmacol. (1989) [Pubmed]
 
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