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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Gadolinium-DTPA-enhanced magnetic resonance imaging in intractable partial epilepsy.

We performed magnetic resonance imaging (MRI), before and after the administration of gadolinium-DTPA (Gd-DTPA), in 23 patients with medically refractory partial epilepsy who subsequently had surgical treatment for their seizure disorder. In most patients, 61%, unenhanced and enhanced MRI studies were negative. In 26% the unenhanced image was positive, and the abnormality enhanced with Gd-DTPA. In 13% the unenhanced MR image was positive, but the abnormality did not enhance with Gd-DTPA. Gd-DTPA does not appear to increase the diagnostic yield of MRI in the presurgical evaluation of patients with partial epilepsy if the unenhanced MRIs are normal.[1]

References

  1. Gadolinium-DTPA-enhanced magnetic resonance imaging in intractable partial epilepsy. Cascino, G.D., Hirschorn, K.A., Jack, C.R., Sharbrough, F.W. Neurology (1989) [Pubmed]
 
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