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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis.

Mitochondrial heat-shock protein hsp60 functions in the folding of proteins imported into mitochondria. Folding occurs at the surface of hsp60 in an ATP-mediated reaction, followed by release of the bound polypeptides. We propose that hsp60 catalyses protein folding.[1]

References

  1. Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis. Ostermann, J., Horwich, A.L., Neupert, W., Hartl, F.U. Nature (1989) [Pubmed]
 
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