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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Impact of new insect growth regulators and their formulations on mosquito larval development in impoundment and floodwater habitats.

Four insect growth regulators were evaluated in the laboratory and field. In the laboratory, AC-291898 showed excellent activity, inducing 90% mortality in Culex quinquefasciatus and Aedes aegypti at 0.5-0.7 ppb. The EC formulation of XRD-473 was slightly more active than the technical material with an LC90 of 0.84 ppb and 0.92 ppb against Ae. aegypti and Cx. quinquefasciatus, respectively. In the field, AC-291898 at the rates of 0.005 and 0.01 lb AI/acre caused 85 and 100% inhibition of adult emergence of Cx. tarsalis 2 days after treatment. Activity, however, declined at the low rate, while the high rate remained active for more than 7 days. In the same species, XRD-473 induced complete inhibition of adult emergence 2 days after treatment at the rates of 0.01, 0.025 and 0.05 lb AI/acre. At the low rate (0.01 lb AI/acre), activity declined markedly, while the 2 higher rates remained active for one week. In Cx. peus larvae, AC-291898 at the rates of 0.005, 0.01 and 0.025 lb AI/acre produced complete inhibition of adult emergence 2 days after treatment, but activity declined at the 2 lower rates 7 days after treatment, while the high rate (0.025 lb AI/acre) remained active for more than one week. Methoprene (4%) pellets were effective against Cx. tarsalis for 7 days at the rates of 0.25 lb AI/acre whereas 0.5 lb AI/acre was required to obtain similar results against Cx. peus larvae.(ABSTRACT TRUNCATED AT 250 WORDS)[1]

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